I guess there's not much you can do except moving the speakers. At 160 Hz the speakers are completely omnidirectional, so the combined direct sound plus reflections would appear to be out of phase. There shouldn't be any issue with the direct sound, so I would try working on the reflections.
This what Google AI says. It agrees with you.
"AI Overview
If you're experiencing a dip in your room's acoustics when using two speakers but not with just one, this is most likely due to a phenomenon called "speaker boundary interference" (SBI), where sound waves from each speaker interfere destructively with reflections bouncing off nearby walls, creating a noticeable dip in the frequency response at certain points in the room, especially when the speakers are positioned too close together.
Key points about SBI and why it might only appear with two speakers:
Interference pattern:
When sound waves from two speakers overlap, they can either reinforce each other (constructive interference) or cancel each other out (destructive interference) depending on the distance and phase relationship between the waves.
Room reflections:
When sound waves hit a wall, they bounce back, and if these reflections reach your ears at the same time as the direct sound from the speaker, it can cause interference.
Speaker placement:
If your speakers are positioned too close to walls or corners, the reflections can be particularly strong and create a noticeable dip in the frequency response at specific frequencies.
How to address the dip:
Adjust speaker positioning:
Move speakers away from walls: Try positioning your speakers further away from walls and corners to minimize reflections.
Experiment with speaker spacing: Adjust the distance between the speakers to find a sweet spot where the interference is minimized.
Speaker height: Ensure your speakers are at ear level for optimal sound dispersion.
Room acoustic treatment:
Acoustic panels: Install sound absorbing panels on walls and ceilings to reduce reflections and improve overall acoustics.
Bass traps: Use bass traps in corners to address low-frequency issues caused by room modes.
Measurement tools:
Room acoustic software: Use a room measurement software like REW (Room EQ Wizard) to identify the exact frequencies where the dip occurs and to fine-tune speaker placement."